Physical examination maneuver

Physical Exam

Capillary Refill

also known as Capillary refill time | CRT | Nail blanch test
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Video coming September 2026

How to Perform

Hold the patient's hand at about heart level. Press firmly on the pad or nail bed of a finger for roughly 5 seconds until it blanches, then release and count the time for the normal color to return.

How to Interpret

Showing 10 of 15 findings

Dehydration

Capillary refill prolonged (>2-3 seconds) in a child
Rule in
Somewhat helpful
Rule out
Minimally helpful
Evidence:Strong

Hemodynamic Instability

Capillary refill time ≥3 seconds before a dialysis session, predicting intradialytic hemodynamic instability
Rule in
Somewhat helpfulDerived CI
Rule out
Minimally helpfulDerived CI
Evidence:Limited

Hypovolemia

Capillary refill time prolonged (greater than 2-3 seconds)
Rule in
Helpful
Rule out
Minimally helpful
Evidence:Limited

Low Cardiac Output

Combination of all 3 findings (cool limbs, capillary refill time >2 seconds, mottling over knees) in an ICU patient, detecting a low cardiac index
Rule in
HelpfulDerived CI
Rule out
Not helpfulDerived CI
Evidence:Limited

Mortality

Capillary refill time ≥3 seconds in an ICU patient with septic shock
Rule in
Somewhat helpful
Rule out
Somewhat helpful
Evidence:Strong
Prolonged capillary refill time (measured at presentation, before fluid resuscitation) in a patient with acute circulatory failure
Rule in
Minimally helpfulDerived CI
Rule out
Minimally helpfulDerived CI
Evidence:Limited
Prolonged capillary refill time in a patient with sepsis and elevated lactate after initial fluid resuscitation
Rule in
Very helpfulDerived CI
Rule out
Minimally helpfulDerived CI
Evidence:Limited
Capillary refill time >3 seconds in an ICU patient with cardiogenic shock
Rule in
Somewhat helpfulNo CI
Rule out
HelpfulNo CI
Evidence:LimitedResearch in progress

Postoperative Complication

Capillary refill time above 4.5 seconds on postoperative day 2 after abdominal surgery
Rule in
Very helpfulDerived CI
Rule out
Somewhat helpfulDerived CI
Evidence:Limited

Shock

Capillary refill prolonged (>3 seconds)
Rule in
Minimally helpfulDerived CI
Rule out
Minimally helpfulDerived CI
Evidence:Strong

References

Research in progress on one or more findings above; ratings may change.

  • Jacquet-Lagrèze M, Pernollet A, Kattan E, Ait-Oufella H, Chesnel D, Ruste M, Schweizer R, Allaouchiche B, Hernandez G, Fellahi JL. Prognostic value of capillary refill time in adult patients: a systematic review with meta-analysis. Crit Care. 2023;27(1):473. doi:10.1186/s13054-023-04751-9. PMID: 38042855. PMC10693708.
  • McGee S, Abernethy WB 3rd, Simel DL. The rational clinical examination. Is this patient hypovolemic? JAMA. 1999;281(11):1022-1029. doi:10.1001/jama.281.11.1022. PMID: 10086438. Free DARE summary at NCBI Bookshelf NBK67823.
  • Khan NA, Rahim SA, Anand SS, Simel DL, Panju A. Does the clinical examination predict lower extremity peripheral arterial disease? JAMA. 2006;295(5):536-546. doi:10.1001/jama.295.5.536. PMID 16449619.
  • Steiner MJ, DeWalt DA, Byerley JS. Is this child dehydrated? JAMA. 2004;291(22):2746-2754. doi:10.1001/jama.291.22.2746. PMID: 15187057.
  • Gutiérrez-Zárate D, Rosas-Sánchez K, Zaragoza JJ. Clinical evaluation of peripheral tissue perfusion as a predictor of mortality in sepsis and septic shock in the intensive care unit: systematic review and meta-analysis. Med Intensiva (Engl Ed). 2023;47(12):697-707. doi:10.1016/j.medin.2023.05.001 (Spanish edition) and doi:10.1016/j.medine.2023.05.011 (English edition, the version PubMed indexes). PMID: 37419840. PROSPERO CRD42019134351.
  • Jacquet-Lagrèze M, Pernollet A, et al. Prognostic value of capillary refill time in adult patients: a systematic review with meta-analysis. Crit Care. 2023;27(1):473. doi:10.1186/s13054-023-04751-9. PMID: 38042855.
  • Lara B, Enberg L, Ortega M, et al. Capillary refill time during fluid resuscitation in patients with sepsis-related hyperlactatemia at the emergency department is related to mortality. PLoS One. 2017;12(11):e0188548. PMID: 29176794.
  • Merdji H, Curtiaud A, Aheto A, et al. Performance of early capillary refill time measurement on outcomes in cardiogenic shock: an observational, prospective multicentric study. Am J Respir Crit Care Med. 2022;206(10):1230-1238. PMID: 35849736.
  • Lima A, Jansen TC, van Bommel J, Ince C, Bakker J. The prognostic value of the subjective assessment of peripheral perfusion in critically ill patients. Crit Care Med. 2009;37(3):934-938. PMID: 19237899.
  • Bigé N, Lavillegrand JR, Dang J, et al. Bedside prediction of intradialytic hemodynamic instability in critically ill patients: the SOCRATE study. Ann Intensive Care. 2020;10(1):47. PMID: 32323060.
  • Grissom CK, Morris AH, Lanken PN, et al. Association of physical examination with pulmonary artery catheter parameters in acute lung injury. Crit Care Med. 2009;37(10):2720-2726. PMID: 19885995.
  • van Genderen ME, Paauwe J, de Jonge J, et al. Clinical assessment of peripheral perfusion to predict postoperative complications after major abdominal surgery early: a prospective observational study in adults. Crit Care. 2014;18(3):R114. doi:10.1186/cc13905. PMID: 24894892.
  • Bige N, Lavillegrand JR, Dang J, Attias P, Deryckere S, Joffre J, et al. Bedside prediction of intradialytic hemodynamic instability in critically ill patients: the SOCRATE study. Ann Intensive Care. 2020;10(1):47. doi:10.1186/s13613-020-00663-x. PMID: 32323060.
  • Fleming S, Gill P, Jones C, Taylor JA, Van den Bruel A, Heneghan C, Roberts N, Thompson M. The diagnostic value of capillary refill time for detecting serious illness in children: a systematic review and meta-analysis. PLoS One. 2015;10(9):e0138155. doi:10.1371/journal.pone.0138155. PMID: 26375953.
  • Gutierrez-Zarate D, Rosas-Sanchez K, Zaragoza JJ. Clinical evaluation of peripheral tissue perfusion as a predictor of mortality in sepsis and septic shock in the intensive care unit: systematic review and meta-analysis. Med Intensiva (Engl Ed). 2023;47(12):697-707. doi:10.1016/j.medin.2023.05.001.
  • Jacquet-Lagreze M, Pernollet A, Kattan E, Ait-Oufella H, Chesnel D, Ruste M, Schweizer R, Allaouchiche B, Hernandez G, Fellahi JL. Prognostic value of capillary refill time in adult patients: a systematic review with meta-analysis. Crit Care. 2023;27(1):473. doi:10.1186/s13054-023-04751-9. PMID: 38042855.
  • Khan NA, Rahim SA, Anand SS, Simel DL, Panju A. Does the clinical examination predict lower extremity peripheral arterial disease? JAMA. 2006;295(5):536-546. doi:10.1001/jama.295.5.536. PMID: 16449619.
  • McGee S, Abernethy WB 3rd, Simel DL. The rational clinical examination. Is this patient hypovolemic? JAMA. 1999;281(11):1022-1029. doi:10.1001/jama.281.11.1022. PMID: 10086438.
  • Merdji H, Curtiaud A, Aheto A, Studer A, Harjola VP, Monnier A, et al. Performance of early capillary refill time measurement on outcomes in cardiogenic shock: an observational, prospective multicentric study. Am J Respir Crit Care Med. 2022;206(10):1230-1238. PMID: 35849736.

Research last updated September 10, 2026.