Physical examination maneuver

Physical Exam

Hand Strength

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How to Perform

Test hand and finger strength against resistance, comparing sides: grip strength (squeezing your fingers), finger abduction, and the pinch between thumb and fingers. Grade the strength and note any pain or give-way weakness.

How to Interpret

Showing 5 of 7 findings

Carpal Tunnel Syndrome

Weakness of thumb abduction (and opposition)
Rule in
Minimally helpful
Rule out
Somewhat helpful
Evidence:Moderate

Cervical Radiculopathy

Weak wrist extension
Rule in
Somewhat helpfulWide CI
Rule out
Not helpfulDerived CI
Evidence:Moderate
Weak finger flexion
Rule in
Somewhat helpfulDerived CI
Rule out
InconclusiveWide CI
Evidence:Moderate

Functional Neurologic Disease

Give-way (collapsing) weakness on resisted strength testing
Rule in
Very helpfulNo CI
Rule out
Somewhat helpfulNo CI
Evidence:Moderate

Malnutrition

Reduced grip strength
Rule in
Not helpfulDerived CI
Rule out
InconclusiveWide CI
Evidence:Moderate

References

Research in progress on one or more findings above; ratings may change.

  • D'Arcy CA, McGee S. The rational clinical examination. Does this patient have carpal tunnel syndrome? JAMA. 2000 Jun 21;283(23):3110-3117. doi:10.1001/jama.283.23.3110. PMID 10865306. (Erratum JAMA. 2000;284(11):1384.)
  • Andrews K, Rowland A, Pranjal A, Ebraheim N. Cubital tunnel syndrome: anatomy, clinical presentation, and management. J Orthop. 2018 Aug 16;15(3):832-836. doi:10.1016/j.jor.2018.08.010. PMID 30140129. (Erratum J Orthop. 2020;23:275.)
  • Kori SH, Foley KM, Posner JB. Brachial plexus lesions in patients with cancer: 100 cases. Neurology. 1981;31(1):45-50. PMID: 6256684.
  • Yoss RE, Corbin KB, MacCarty CS, Love JG. Significance of symptoms and signs in localization of involved root in cervical disk protrusion. Neurology. 1957;7(10):673-683. PMID: 13477342.
  • Alamri SH, Simbawa MM. The clinical utility of handgrip strength as a malnutrition screening tool in hospitalized older adults: a cross-sectional study in Saudi Arabia. Front Med (Lausanne). 2024;11:1436977. doi:10.3389/fmed.2024.1436977. PMID: 39109223. PMCID: PMC11301408 (open access).
  • Daum C, Hubschmid M, Aybek S. The value of 'positive' clinical signs for weakness, sensory and gait disorders in conversion disorder: a systematic and narrative review. J Neurol Neurosurg Psychiatry. 2014 Feb;85(2):180-190. doi:10.1136/jnnp-2012-304607. PMID 23467417.
  • Bickley LS, Szilagyi PG, Hoffman RM, Soriano RP. Bates' Guide to Physical Examination and History Taking. 13th ed. Philadelphia, PA: Wolters Kluwer; 2021.
  • Swartz MH. Textbook of Physical Diagnosis: History and Examination. 9th ed. Philadelphia, PA: Elsevier; 2025.

Research last updated September 9, 2026.