Physical examination maneuver

Physical Exam

Nystagmus Characterization

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How to Perform

Observe the eyes with the patient looking straight ahead and then holding gaze to the right, left, up, and down (avoid extreme end-gaze, which can produce normal end-point nystagmus). Note whether involuntary oscillation is present, its plane (horizontal, vertical, torsional, or mixed), the direction of the fast phase, whether it is present at rest or only on gaze, and whether it changes direction with the direction of gaze.

How to Interpret

Showing 4 of 5 findings

Stroke

HINTS exam concerning (central pattern) in a patient with acute vestibular syndrome
Rule in
Helpful
Rule out
Very helpful
Evidence:Strong
Nystagmus present in a patient with confirmed acute ischemic stroke
Rule in
Very helpfulDerived CI
Rule out
Not helpfulDerived CI
Evidence:Moderate

Vestibular Dysfunction

Purely vertical (down-beating or up-beating), purely torsional, or vertical-torsional spontaneous nystagmus
Rule in
Helpful
Rule out
Not helpful
Evidence:Strong
HINTS exam reassuring (peripheral pattern) in a patient with acute vestibular syndrome
Rule in
Very helpfulDerived CI
Rule out
Very helpfulDerived CI
Evidence:Moderate

References

  • Newman-Toker DE, Kerber KA, Hsieh YH, Pula JH, Omron R, Saber Tehrani AS, et al. HINTS outperforms ABCD2 to screen for stroke in acute continuous vertigo and dizziness. Acad Emerg Med. 2013;20(10):986-996. doi:10.1111/acem.12223. PMID: 24127701.
  • Ooi S, Phillips G, Tang T, Chen L, Fok A, Ly J, Ma H, Phan TG. Meta-Analysis of the Use of Head Impulse Test and Head Impulse Test with Direction Changing Nystagmus and Test of Skew Deviation in the Diagnosis of Peripheral Vertigo and Stroke. Cerebrovasc Dis. 2023;52(2):184-193. doi:10.1159/000526331. PMID: 36088909.
  • Tao WD, Liu M, Fisher M, Wang DR, Li J, Furie KL, et al. Posterior versus anterior circulation infarction: how different are the neurological deficits? Stroke. 2012;43(8):2060-2065. doi:10.1161/STROKEAHA.112.652420. PMID: 22678088.
  • Wüthrich M, Wang Z, Martinez CM, Carmona S, Mantokoudis G, Tarnutzer AA. Systematic review and meta-analysis of the diagnostic accuracy of spontaneous nystagmus patterns in acute vestibular syndrome. Front Neurol. 2023;14:1208902. doi:10.3389/fneur.2023.1208902. PMID: 37396773.
  • Bickley LS, Szilagyi PG, Hoffman RM, Soriano RP. Bates' Guide to Physical Examination and History Taking. 13th ed. Philadelphia, PA: Wolters Kluwer; 2021.
  • Swartz MH. Textbook of Physical Diagnosis: History and Examination. 9th ed. Philadelphia, PA: Elsevier; 2025.

Research last updated September 9, 2026.