Physical examination maneuver

Physical Exam

Spleen Palpation

🎬
Video coming September 2026

How to Perform

With the patient supine, stand at the right side and reach across with your left hand to support and gently lift the lower left rib cage from behind. Place your right hand flat on the abdomen, beginning in the right lower quadrant. Press gently inward and upward as the patient takes a deep breath, feeling for the splenic edge to descend against your fingers. If no edge is felt, move your right hand diagonally toward the left upper quadrant in small increments, repeating the maneuver with each inspiration until you reach the left costal margin.

How to Interpret

Showing 4 of 17 findings

Cirrhosis

Palpable spleen tip
Rule in
Somewhat helpful
Rule out
Not helpful
Evidence:Strong

Infectious Mononucleosis

Palpable spleen tip in an adolescent or young adult
Rule in
Somewhat helpful
Rule out
Minimally helpful
Evidence:Strong

Malaria

Palpable spleen in returning travelers with fever
Rule in
Helpful
Rule out
Not helpful
Evidence:Strong

Splenomegaly

Palpable spleen tip
Rule in
Very helpfulDerived CI
Rule out
Minimally helpfulDerived CI
Evidence:Limited

References

  • Dubey S, Swaroop A, Jain R, Verma K, Garg P, Agarwal S. Percussion of Traube's space--a useful index of splenic enlargement. J Assoc Physicians India. 2000;48(3):326-328. PMID: 11229121.
  • Cai X, Ebell MH, Haines L. Accuracy of Signs, Symptoms, and Hematologic Parameters for the Diagnosis of Infectious Mononucleosis: A Systematic Review and Meta-Analysis. J Am Board Fam Med. 2021 Nov-Dec;34(6):1141-1156. doi:10.3122/jabfm.2021.06.210217. PMID 34772769.
  • Ben-Baruch S, Canaani J, Braunstein R, et al. Predictive parameters for a diagnostic bone marrow biopsy specimen in the work-up of fever of unknown origin. Mayo Clin Proc. 2012;87(2):136-142. PMID: 22226833.
  • Udell JA, Wang CS, Tinmouth J, FitzGerald JM, Ayas NT, Simel DL, Schulzer M, Mak E, Yoshida EM. Does this patient with liver disease have cirrhosis? JAMA. 2012;307(8):832-842. doi:10.1001/jama.2012.186. PMID: 22357834.
  • Lucijanic M, Krecak I, Soric E, et al. Palpable spleen size is differently prognostic in primary and secondary myelofibrosis. Leuk Lymphoma. 2023;64(4):893-896. PMID: 36799562.
  • Taylor SM, Molyneux ME, Simel DL, Meshnick SR, Juliano JJ. Does this patient have malaria? JAMA. 2010;304(18):2048-2056. PMID: 21057136.
  • Schenker S, Balint J, Schiff L. Differential diagnosis of jaundice: report of a prospective study of 61 proved cases. Am J Dig Dis. 1962;7(5):449-463. PMID: 13991584.
  • Williamson HA. Lymphadenopathy in a family practice: a descriptive study of 249 cases. J Fam Pract. 1985;20(5):449-452. PMID: 3989485. Corroborating closest candidate: Vassilakopoulos TP, Pangalis GA. Medicine (Baltimore). 2000;79(5):338-347. PMID: 11039082.
  • McGee S. Evidence-Based Physical Diagnosis. 6th ed. Philadelphia, PA: Elsevier; 2025.

Research last updated September 10, 2026.