Physical examination maneuver

Physical Exam

Thyroid Palpation

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How to Perform

Standing behind or in front of the seated patient with the patient's neck slightly flexed, gently place the pads of your fingers at the base of the anterior neck in the spaces between the trachea and the sternocleidomastoid muscles bilaterally. Ask the patient to swallow (offer a sip of water if needed) and feel the gland rise with the swallow. Note the size, symmetry, consistency, nodularity, and tenderness.

How to Interpret

Showing 8 of 15 findings

Chronic Obstructive Pulmonary Disease

Maximum laryngeal height ≤4 cm
Rule in
Somewhat helpful
Rule out
Minimally helpful
Evidence:Moderate
Laryngeal descent >3 cm
Rule in
Not helpful
Rule out
—
Evidence:Moderate

Goiter

Palpably enlarged thyroid (goiter)
Rule in
Somewhat helpfulNo CI
Rule out
Somewhat helpfulNo CI
Evidence:Moderate

Thyroid Carcinoma

Thyroid nodule, very firm nodule
Rule in
Very helpfulDerived CI
Rule out
Not helpfulDerived CI
Evidence:Moderate
Firm or hard nodule on palpation
Rule in
Somewhat helpfulDerived CI
Rule out
HelpfulDerived CI
Evidence:Moderate
Thyroid nodule or goiter fixed to surrounding tissues (does not move on swallowing)
Rule in
Somewhat helpfulDerived CI
Rule out
Not helpfulDerived CI
Evidence:Moderate
Thyroid nodule/goiter fixed (fixation) to surrounding tissues
Rule in
Somewhat helpfulDerived CI
Rule out
Not helpfulDerived CI
Evidence:Moderate

Thyroid Nodule

Palpable solitary thyroid nodule
Rule in
Not helpfulDerived CI
Rule out
Not helpfulDerived CI
Evidence:Moderate

References

Research in progress on one or more findings above; ratings may change.

  • Soto Jacome C, Garcia A, Golembiewski E, Loor-Torres R, Duran M, Segura D, Toro-Tobon D, Fan JW, Singh Ospina N, Brito JP. Physical examination of the thyroid: accuracy in detecting thyroid nodules and frequency of additional findings. Endocr Pract. 2024;30(1):31-35. doi:10.1016/j.eprac.2023.10.002. PMID: 37805101.
  • Cañete EJ, Sison-Peña CM, Jimeno CA. Clinicopathological, biochemical, and sonographic features of thyroid nodule predictive of malignancy among adult Filipino patients in a tertiary hospital in the Philippines. Endocrinol Metab (Seoul). 2014;29(4):489-497. doi:10.3803/EnM.2014.29.4.489. PMID: 25325270. PMCID: PMC4285043.
  • Campanella P, Ianni F, Rota CA, Corsello SM, Pontecorvi A. Quantification of cancer risk of each clinical and ultrasonographic suspicious feature of thyroid nodules: a systematic review and meta-analysis. Eur J Endocrinol. 2014;170(5):R203-R211. PMID: 24536085.
  • Cotter A, Jinih M. Thyroid nodule size and risk of malignancy: a systematic review. Discov Oncol. 2025;16:1188. doi:10.1007/s12672-025-02588-y. PMID: 40591129. PMCID: PMC12214072.
  • Kuru B, Gulcelik NE, Gulcelik MA, Dincer H. Predictive index for carcinoma of thyroid nodules and its integration with fine-needle aspiration cytology. Head Neck. 2009;31(7):856-866. PMID: 19340874.
  • Straus SE, McAlister FA, Sackett DL, Deeks JJ. The accuracy of patient history, wheezing, and laryngeal measurements in diagnosing obstructive airway disease. CARE-COAD1 Group. JAMA. 2000;283(14):1853-1857. doi:10.1001/jama.283.14.1853. PMID: 10770147.
  • Fatourechi V, Aniszewski JP, Fatourechi GZE, Atkinson EJ, Jacobsen SJ. Clinical features and outcome of subacute thyroiditis in an incidence cohort: Olmsted County, Minnesota, study. J Clin Endocrinol Metab. 2003;88(5):2100-2105. PMID: 12727961.
  • Trzepacz PT, Klein I, Roberts M, Greenhouse J, Levey GS. Graves' disease: an analysis of thyroid hormone levels and hyperthyroid signs and symptoms. Am J Med. 1989;87(5):558-561. PMID: 2816972.
  • Siminoski K. Does this patient have a goiter? JAMA. 1995;273(10):813-817. doi:10.1001/jama.1995.03520340069039. PMID: 7861577.
  • Cañete EJ, Sison-Peña CM, Jimeno CA. Clinicopathological, biochemical, and sonographic features of thyroid nodule predictive of malignancy among adult Filipino patients in a tertiary hospital in the Philippines. Endocrinol Metab (Seoul). 2014;29(4):489-497. doi:10.3803/EnM.2014.29.4.489. PMCID: PMC4285043.
  • Carrillo JF, Frias-Mendivil M, Ochoa-Carrillo FJ, Ibarra M. Accuracy of fine-needle aspiration biopsy of the thyroid combined with an evaluation of clinical and radiologic factors. Otolaryngol Head Neck Surg. 2000;122(6):917-921. PMID: 10828810.
  • Chiofalo MG, Signoriello S, Fulciniti F, Avenia N, Ristagno S, Lombardi CP, et al. Predictivity of clinical, laboratory and imaging findings in diagnostic definition of palpable thyroid nodules. A multicenter prospective study. Endocrine. 2018;61(1):43-50. doi:10.1007/s12020-018-1577-5. PMID: 29569123. PMCID: PMC5997121.

Research last updated September 10, 2026.